What are cancer clinical trials?

What Do We Need To Know About Cancer?
September 6, 2018

What are cancer clinical trials?

Why It is important for cancer patients to go through cancer clinical trials?

Cancer clinical trials are research studies that aim to find new and effective ways to treat cancer and clinical trials also target the early diagnosis of cancer. Through these trials, oncologists can find new approaches to potentially cure cancer of different stages. Trials can be in a form of new and/or established therapies, drug combinations or new sets of drugs for every type and stage of cancer. Aiming
also to find possible ways to reduce side effects, to give cancer patients the highest quality of treatment and to stop cancer recurrence. Clinical labs are keeping their strategies up to date with the newest research studies. Cancer clinical trials are not only for cancer patients, clinical trials are conducted for cancer prevention.

Cancer Clinical Trials: Four Phases


Once a drug is approved for human studies, it is tested in a small trial to determine the optimal safe dose. Phase I studies often involve patients with different kinds of cancer, or more recently, a single genetic change.


If a drug can be given safely to people on the Phase I trial, it is tested in a Phase II study. These are larger studies, usually for one or more specific types and stages of cancer. The goal of Phase II studies is to both determine the optimal dosing and provide an early assessment of whether the drug works.


These trials take place after a drug has shown good results in earlier studies. They are large studies, often involving hundreds, or even thousands of patients, in multiple centers in the United States and/or abroad. Patients on Phase III trials have specific types and stages of cancer. Many Phase III trials are randomized—meaning that patients are randomly assigned to receive either the new treatment or the established standard of care. These trials are designed to provide definitive evidence to support FDA approval of the drug or agent for use in the public.


These trials take place after a drug is approved and are often called post-marketing trials. The goal is to make sure that no safety or other concerns come up after a drug is approved that may not have been seen in the pre-approval trials. It is important to follow patients for a number of years to determine if there are any long-term side effects or other issues that affect the way the treatment is used.

Cancer clinical trials help find new ways to detect cancer and help improve the quality of life for people during and after treatment.To have a better understanding about cancer and to have the knowledge about cancer care for future patients, be clinically tried.
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